Federrath's research focuses on understanding the formation of stars in the Universe. Almost everything we know about the Universe comes from observing star light. The formation of stars controls galaxy evolution and sets the initial conditions for planet formation. To advance our understanding of star formation, Federrath develops theoretical models and supercomputer simulations of molecular clouds, the birthplaces of stars. This involves the physics of turbulence, gravity, magnetic fields, radiation, stellar feedback and chemical evolution. An essential part of this work is to compare supercomputer simulations performed on thousands of computer cores to real observations in galactic clouds. The ultimate goal of Federrath's research is to establish a model that combines all the relevant physics and chemistry to enable self-consistent comparisons with observations and to provide powerful predictions for how galaxies, stars and planets form in the Universe.